FIP treatment

Before the Treatmnet
Parents will take the cat to the hospital for diagnosis before FIP treatment. After Feline Infectious peritonitis is diagnosed, we can usually do something to help the cat relieve its pain, such as taking some fluid to relieve breathing difficulties, accompanying them, and manually feeding.

Extract effusion and protein supplement
There will be effusion in the chest and abdomen of the wet FIP cats, so the liquid is drawn away, but the amount of liquid drawn should be less than 1/3. After a few pages are extracted, the cat will feel more comfortable and breathe more smoothly.
These effusions will reappear, and fluids need to be pumped at this time-so repeatedly, a lot of protein will be lost. Therefore, in food selection, we must pay special attention to high-protein foods, such as canned food and meat.

Manual feeding
Sick cats have poor appetite and energy, and are less likely to take the initiative to eat. At this time, try to provide the cat with the food that he likes to eat, and hand it to the mouth to feed it often results in good results. Some doctors will prescribe “prescription food”. Prescription food has no meaning for infectious peritonitis. If your cat doesn’t like it, don’t eat it.

Companion and environment
The cat is sick and very sick. He needs a quiet and comfortable environment. Avoid noisy environments and strangers, cats, and dogs. Most of the cats at this time are more clingy than ever, stay with him more, even chat with him, even if he doesn’t understand what you say.

During the Treatment

The treatment should be started as soon as possible, and the kittens less than 3 months old should be treated with medication within 1-2 days as far as possible,better to not wait for the blood test results.
Treatment is a long journey, but FIP is tricky. Parents need to pay extra attention to the cat’s health and take every right step to do their best to treat amd reduce the relapse rate.
Parents should keep close communication with administrators, veterinarians and related professionals about cat, and do not treat cats by themselves.

√√  Main medication

♥ Lucky GS441
GS is short for GS-441524, a small molecule nucleotide analogue. It is found that it has a specific effect on FIP by Perdersen NC of UC Davis (Global Veterinary No.1) and his scientific research theme of feline infectious peritonitis . It is a reverse transcriptase inhibitor that can inhibit the replication of feline abdominal virus (FIP), and is a prerequisite molecule for the synthesis of nucleoside triphosphates with pharmacological activity.

In the synthesis of FIPV virus RNA, GS-441524 is phosphorylated into active NTP through a series of cellular kinases in the cell, competing to participate in the transcription of cat coronavirus RNA, thereby inhibiting virus proliferation in the body.

»Injection method
Subcutaneously injection once a day(the shot should be given at the same time every day)
Rotate injection sites every day to allow them to heal, and AVOID the scruff and spine areas entirely

»Treatment dosage
The specific dosage (GS-441524) depends on the specific symptoms of the cat.
Wet FIP: 0.4ml/kg/d ( 6 mg/kg/day) subcutaneously.
Dry FIP: 0.4ml/kg/d (7 mg/kg/day) subcutaneously.
Ocular FIP: 0.7 ml/kg/d (8 mg/kg/day) subcutaneously

Neuro FIP: 0.8ml/kg/d (10 mg/kg/day) subcutaneously.
Note: Calculation based on the standard concentration of GS-441524 at 20 mg/ml, the dosage should be adjustd appropriately according to the health condition. The dosage needs to be increased when the symptoms become worse or the weight gains.
Note : Dosage recommended not to be less than 6 mg/kg/day).

1.Do notinject in the cat’s scuff,it’s slow toabsorb and the area is not big enough for all the injections.
2.Subcutaneous injections can be given along the shoulders area left and right ofthe spine. For better visibility it’s advised to shave the area
3.Avoid if possible the butt’s area, it’s a particularly sensitive area, it can be more painful.

»Treatment Period
The recommended treatment period is 12 weeks. According to reports in the literature, the cure rate after 12 weeks of treatment is about 96%. According to the individual differences of cats, the recommendation is subject to the blood and biochemical panels tests  results.

√√  Auxiliary medication

Adjuvant medication is not a necessary medication for FIP treatment. It is recommended that parents choose the medicine they need according to the health of the cat. Check regularly (once every 4 weeks) to make a blood biochemical test report, and select supplementary medications based on indicators.

Cats could take corticosteroid anti-inflammatory drugs such as prednisone and prednisolone when wait for the GS medicine, then decrease the dosage gradually until stop the prednisone,  However, unlike treating enteritis, acute inflammation, and fighting against malignant diseases such as FIP, hormone drugs are not as effective as they used to be. After using hormone anti-inflammatory drugs, sick cats will immediately get relief. But In fact, it is not that prednisone is effective in treating FIP, but it can reduce and prevent the response of organs and tissues to inflammation and reduce inflammatory exudation.

♦Nutrition and immunity
Cats will have fever and anorexia at the early stage of FIP, which will lead to malnutrition and low immunity. Therefore, it is especially important to ensure that the body gets enough nutrition and improve the body’s immunity during treatment. Severe anorexia occurs at the initial stage. When anorexia is improved, it is necessary to perform forced feeding, that is, to feed (canned food, nutrient solution, nutrient ointment). After the anorexia returns to normal, do not interrupt the nutrient solution, nutrient ointment, canned food and other nutrients. In terms of immunity, sheep placenta transfer can be used. factor.

♦Blood supplement
Anemia is one of the common symptoms of FIP cats, blood supplements must be used, and some related drugs that stimulate blood production.

♦Liver and kidney function
Both the cause of FIP disease and long-term medication are a relatively large burden on the liver and kidneys. Therefore, liver and kidney problems should not be ignored during treatment. Liver protection and prevention of renal failure are particularly important. Please check the liver and kidneys every 4 weeks.

♦Mixed infection and secondary infection
Either mixed infection or secondary infection is the cause for FIP cats to pass away. Often the death of cats is not due to FIP itself, but mixed infections and secondary infections are causing trouble. This is why some parents have FIP symptoms during treatment. The key to alleviating some symptoms such as fever, anorexia, etc., is especially important to prevent viral and bacterial infections during treatment. It is recommended to use some interferons and antibiotics (cephalosporins are not recommended) to prevent mixed infections or secondary infections, if conditions permit Parents recommend checking blood routine and biochemistry once a week. First, you can monitor the recovery of various indicators of the body. Second, you can also monitor whether there are other infections.

♦Intestinal medication
Because the coronavirus first invades the intestines, some cats will have diarrhea. It is recommended that yeasts cooperate with probiotics to regulate the intestines and stomach. In the case of intestinal mucosal damage (pulling blood, the mucous membrane is pulled out). Treat with slippery elm peel powder. For cats with severe watery diarrhea, montmorillonite powder can be used.

Vitamins have too many effects on cats. Sufficient vitamin intake is beneficial to both sick FIP cats and healthy cats. It is recommended to supplement it during the treatment period, which will greatly benefit the treatment and body recovery. Benefits (ask Google for specific benefits)

Type of FIP injections 20mg/ml(ml/kg/day)
Type of FIP pills (active mg/kg/day)
LD stand for Last Dose

Cat Weight(kg)

Daily volume: